Smo Agonist, SAG for cell activation

Smo Agonist, SAG for cell activation
Size
1 mg
Catalog no.
1939-1000
Price
316 EUR
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Is this a salt?

No

Is it cell-permeable?

Yes

Peptide sequence

N/A

Supplied with

N/A

Tissue

cell

Reconstitute instructions

DMSO

Storage condition

-20°C

Molecular weight

490.06

Shipping condition

gel pack

Maximum time for storage

36 months

Physical appearance

White solid

CAS number

912545-86-9

Category

Biochemicals

Purification

≥98% by NMR

Storage instructions

Protect from light

Molecular formula

C₂₈H₂₈ClN₃OS

Additional description

For cells, cell lines and tissues in culture till half confluency.

Other name

N-Methyl-N′-(3-pyridinylbenzyl)-N′-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane

Description

Cell-permeable. A Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.